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139,140 Adiponectin activates the AMPK and PPAR- signaling pathways through adiponectin receptor 1 (AdipoR1) and AdipoR2 respectively, leading to enhanced fatty acid oxidation and glucose uptake in muscle, along with suppressed gluconeogenesis in liver tissues

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Eriksson L, Saxelin R, Rhl S, Roy J, Caidahl K, Nystrm T, et al