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Across the trials, the absolute risk differences (ARD) between intervention and placebo groups were minimal, generally ranging from 0.9% to + 0.9%, indicating no consistent increase in risk with GLP-1 receptor agonists

This distinction becomes particularly relevant during acute oxidative challenges, in tissues with low enzymatic antioxidant expression, or in individuals with genetic polymorphisms affecting enzyme function

In comparison, most manufacturers recommend storing lyophilized powder at a lower temperature, away from bright light

Organs 43 , 478489 (2019)

In such cases, supplementation is often recommended