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While strategies such as vitamin supplementation and food fortification are considered promising approaches to mitigate these deficiencies, further research is recommended to develop targeted public health interventions (328)

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Statins target hepatocytes and inhibit HMGCR by competing with its normal substrate at the active site of the enzyme

Indeed, it is intriguing to speculate that the clinical benefit of sorafenib observed in patients may be due, at least in part, to the activation of ferroptosis in vivo [28]

Here Glutathione takes over this process, recycling and reactivating them, in order to make them functional for their neutralizing "scavenger" activity