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The reasons cited by the FDA included concerns about immunogenicity, peptide impurity characterization challenges, and the lack of adequate safety data from human clinical trials

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The parent proteins of these proteoforms underwent GO analysis, to define functional interconnections between highlighted proteins

The working hypothesis was straightforward: if biological ageing reflects a gradual decline in these endogenous peptide signals, then reintroducing them under controlled research conditions might offer insight into the mechanisms of cellular ageing itself

High B12 levels do not typically cause changes in blood sugar