however, emerging studies have found this complication to be uncommon and recommend concomitant therapies
found that the infection degree of Omicron on Calu-3 (a lung cell line, whoseTMPRSS2 expression is normal, but lack of CTSL expression, hindering the nuclear endosome pathway of virus entry) is weaker than Delta, indicating that Omicron entry is more dependent on the nuclear endosome mediated endocytosis pathway 147 rather than the membrane fusion pathway involved in TMPRSS2, and TMPRSS2 is mainly distributed in human lung epithelial cells
The 2025 IV pilot (Lee & Burgess, n=2) found no changes in cardiac, hepatic, renal, thyroid, or glucose markers: but this was n=2 over 2 days, not sustained community-use dosing
There is also legitimate concern for lean mass loss if protein intake and resistance training arent maintained
Practical tips Many side effects can be improved by adjusting your daily routine