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RNA, protein, and enzymatic evidence A global downregulation of the expression of genes encoding mitochondrial proteins, such as those encoding mitochondrial electron transport chain (ETC) components for ATP production, has been reported in postmortem prefrontal cortex samples of BD patients receiving pharmacological treatment [46]

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For instance, you may find yourself having trouble focusing or making decisions, feeling easily irritated, and experiencing slowed reaction times, according to the Sleep Foundation