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They found that people with high levels of both L-carnitine and TMAO were prime targets for heart disease and stroke

Mutations in the superoxide dismutase enzyme (which stabilizes superoxide radicals and is implicated in the pathology of certain kinds of ALS) can decrease its affinity for zinc and cause it to become toxic to motor neurons

And there are some worries about side-effects (nausea, diarrhoea, vomiting, and constipation), and safety concerns (as with any new drug) which need to be dealt with before it becomes certified for use

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If youre experiencing nausea, vomiting, or diarrhea on tirzepatide, your risk of dehydration is even higher , so make sure youre drinking plenty of water to avoid serious side effects like kidney problems or severe hypoglycemia (low blood sugar)