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Cardiovascular disease remains the leading cause of death among people with obesity, with overlapping drivers including insulin resistance, dyslipidemia, inflammation, sleep apnea, and hemodynamic load

-Fabian Gabriel Alizaidy, MD, MS I agree with this a lot because good medicine starts with clinical judgment and science, not headlines

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The primary outcome (a composite of cardiovascular death, non-fatal myocardial infarction, non-fatal stroke, or hospitalization for unstable angina) occurred in 839 patients in the sitagliptin group (11.4%) and 851 patients in the placebo group (11.6%), which was not significantly different