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Symptoms can include rash, itching, swelling, or trouble breathing

What to Expect with Retatrutide Retatrutide is administered as a once-weekly subcutaneous injection

4 Another study in obese male rats found that while a calorie-reduced diet alone led to decreased trabecular thickness and impaired bone remodeling in the tibia and spine, adding moderate treadmill exercise improved tibial BMD and reduced bone resorption, as shown by lower CTX levels and fewer osteoclasts

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