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In the case of an odorless drug or a drug that is difficult to detect via odor, other ways to spot drug abuse in a family member include: : Disinterest in regular friends and relationships Hanging out with new people who use drugs Stopping to engage in usual hobbies, activities, and responsibilities Staying out of the house late at night Being agitated, angry, and hostile Exhibiting anxiety or depression Extreme mood swings (high when on drugs and low during withdrawal) Being secretive, lying, and stealing Lacking coordination, balance, and impulse control Experiencing insomnia and unhealthy sleep hygiene Sudden weight loss, weight gain, or changes in eating pattern Red eyes, dilated pupils, and constant runny nose Decline in personal hygiene, grooming, and appearance If you identify some of these signs in your loved one, they could be using drugs and may already be addicted