A site that was perfect at your starting weight may have insufficient tissue depth after significant weight loss
EBioMedicine 63:103202 Armstrong MJ, Gaunt P, Aithal GP, Barton D, Hull D, Parker R, Hazlehurst JM, Guo K, LEAN trial team, Abouda G, Aldersley MA, Stocken D, Gough SC, Tomlinson JW, Brown RM, Hbscher SG, Newsome PN, (2016) Liraglutide safety and efficacy in patients with non-alcoholic steatohepatitis (LEAN): a multicentre, double-blind, randomised, placebo-controlled phase 2 study
Liraglutide and exendin-4 are initially antidiabetic drugs but can affect tumorigenesis, suggesting GLP-1R agonists as a potential treatment for different cancers as found in vivo (Table 2)
Specifically, GL-0001 represents a first-in-class dual-acting GIP/GLP-2 peptide that improves bone biomechanical properties, preserves trabecular bone structure as well as increasing collagen cross-linking
GLP-1 Agonist Complications