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J Clin Oncol 2014

However, if fluids are administered too rapidlyespecially in individuals with heart or kidney concernssymptoms like headache, nausea, swelling, or shortness of breath can occur

In vitro studies using NRAS -mutated melanoma cells suggested that combined exposure to trametinib and azacitidine postponed the development of trametinib resistance in NRAS -mutated melanoma cells

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