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(2013), Guidance for industry and FDA staff

Under normal circumstances, IL-11 participates in regulating immune responses, but excessive levels can trigger unnecessary inflammation

In mitochondria, DHODH can reduce CoQ to ubiquinol (CoQH2), reducing oxygen free radicals, inhibiting the generation of phospholipid hydroperoxide (PLOOH), and inhibiting phospholipid peroxidation, thereby inhibiting ferroptosis

LOX-12 and LOX-15 also contribute to oxidative stress and depletion of glutathione (GSH), further increasing lipid peroxides

Together, these ingredients help refresh, cleanse, and revive the skin for a visibly brighter and revitalized look