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An evolutionarily favorable fact is that one-half of your B12 is stored in your liver, and it takes many years for these stores to be depleted

[35] Cardiometabolic disease outcomes [edit] Multiple studies have explored the association between vitamin B 12 and metabolic disease outcomes, such as obesity, insulin resistance and the development of cardiovascular disease

Freezing can degrade the formulation so do not freeze it

3 Vegans and vegetarians may also require B12 treatment, especially vegan women who are pregnant or breastfeeding

If youve had a gastric bypass, have a history of Celiac disease or pancreatic deficiencies, or are on a vegan diet, you are also at risk, Yourman says