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FAK phosphorylation initiates signaling affecting cell survival, proliferation, migration

The pathophysiologic mechanisms underpinning S-AKI are complex, and recent studies have shown that acute tubular necrosis, oxidative stress (7), mitochondrial dysfunction, inflammatory responses (8), microvascular dysfunction (9), and ischemia are involved (Figure 1)

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However, this is only one aspect of treatment, and your physician will tell you whether its the right choice for you or not