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The factors that lead to depletion of glutathione includes natural ageing process, or the external stressors that include chronic exposure to chemical toxins, cadmium exposure, alcohol use, smoking, pollution, strenuous aerobic activities, dietary factors, ultraviolet (UV) radiation exposure, tissue injury as from burns, ischemia, septic shock, surgery, drugs (such as acetaminophen and adriamycin)

This study aimed to evaluate the biological activity of newly synthesized triazolediquinothiazine derivatives in colorectal cancer cells and to identify the most promising lead compound for further development

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