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In the STEP 1 trial, participants receiving semaglutide 2.4 mg weekly experienced significant reductions in triglycerides (mean decrease of 15-20%) and total cholesterol compared with placebo

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Long-term extension studies confirm sustained weight maintenance when semaglutide shots treatment continues beyond initial trial durations

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Strategy 7: Gentle desensitization Deliberately exposing sensitive skin to controlled, gentle stimulation can help recalibrate nerve responses