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Perfil de seguridad El perfil de seguridad de Retatrutida documentado en estudios clnicos publicados (Jastreboff 2023, Rosenstock 2023) se concentra en eventos gastrointestinales mediados por agonismo GLP-1 central: Eventos gastrointestinales (frecuencia alta): nusea, vmito, diarrea y estreimiento, dosis-dependientes y mayoritariamente leves a moderados, con incidencia mxima durante las primeras semanas de titulacin