Eli Lilly, the company behind Mounjaro and Zepbound, is the Indiana Fever's "jersey patch and health equity partner." The company had an ad campaign that cautioned against using these drugs for purely aesthetic reasons, saying, Some people have been using medicine never meant for themfor the smaller dress or tux, for a big night, for vanity. The implication is that the drugs are meant for people who need them, and the people who need them, the ad specifies, are people whose health is affected by ob*sity. I want to be clear that semaglutides and other GLPs do offer significant health benefits to folks with diabetes and other metabolic conditionsthis is not what Im talking about
Currently, there are three FDA-approved semaglutide products: Ozempic, Wegovy, and Rybelsus
PlexusDx sources semaglutide compounds exclusively from 503A providers that undergo routine inspections and maintain certificates of analysis for every batch
PAs direct effects on the CNS are not fully clear, with some studies suggesting it might have mild neuroprotective effects, while others indicate it induces inflammation [35, 36]
Figure 1: The increase in type 2DM and cardiovascular death