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They are not sustainable, which leads to regain, often more than what was lost

It activates the Akt survival pathway, recruits stem cells to injury sites, promotes endothelial cell differentiation for angiogenesis, and upregulates matrix metalloproteinases for tissue remodeling

Perhaps, most importantly, when GSH does its job in detoxifying oxidants, the end productwhich is oxidized GSH and is written chemically as GSSH (also called glutathione disulfide)is not itself harmful and is safely and quickly recycled back to GSH