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Indeed, if it is ever demonstrated that gliT expression occurs in the absence of gli cluster expression/gliotoxin biosynthesis (as has been demonstrated herein for A

in the collection, analysis, and interpretation of data

However, it must be pointed out that malignant transformation takes time, and if the patient goes to an oncosurgeon or oncologist, it may not always reflect as long-term complications in dermatological practice

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The gut microbiome also affects the immune system, with ALS patients showing increased Th17 immune cells and higher levels of IL-17, an inflammatory cytokine that may worsen the disease (Zang et al., 2023)