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V.MurilloR.et al (2020a)

We achieved maximum R/R 2 of 0.39/0.12 and 0.32/0.09 using amino acid composition of 5 N-terminal and 5 C-terminal residues, respectively (Table 1)

Gurunathan S, Han JW, Kim J-H

Brutons tyrosine kinase is required for TLR2 and TLR4-induced TNF, but not IL-6, production

Structurally the basis of thiamine action and activation of all ThDP-dependent enzymes lies in thiamine catalysis and deprotonation of the thiazolium ring and contribution of the aminopyrimidine side chain in this effect [197-198] while the pyrimidine ring with its dual proton donor and acceptor capability functioning as a proton transfer system