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With a pKa of 4.56, valproate, the carboxylate moiety of Valproic acid, is highly ionized, at physiological pH 7.42

doi: 10.1016/j.diabet.2019.101117

It is a two-substrate enzyme catalyzing the transfer of -glutamyl moiety from donor substrates, such as glutathione/glutamine, to an acceptor substrate, which can be water (hydrolysis) or other amino acids/small peptides (transpeptidation) or the donor itself (autotranspeptidation) (Thompson and Meister, 1977

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I sometimes eat a handful on their own or mix them into a salad. "I first tried this drink at an event a few months ago and was pleasantly surprised at how delicious it was," says associate editor Kamari Stewart