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[71] Serendipity is said to have played a role in this discovery

Mitochondrial dysfunction, oxidative stress, and cardiac hypertrophy have been observed in laboratory animals on a high-fat and sucrose diet

The early history of GIP 1969-2000: From enterogastrone to major metabolic hormone

They primarily act as catalysts for enzyme actions while some metallic ions take part in oxidation-reduction reactions involved in energy metabolism [2]