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Characterized by insulin resistance, gradual progressive loss of insulin secretion by -cells, and being heavily driven by being overweight or obese [98], T2DM leads to hyperglycemia, excessive urine production, increased risk of cardiovascular disease, and changes in energy metabolism [106]

Preclinical studies strongly support the efficacy of ferroptosis inhibitors (e.g., liproxstatin-1, ferrostatin-1), iron chelators, and Nrf2 activators in mitigating COPD features

Potassium Sorbate A natural material used as a preservative to prevent yeast and mold growth

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Baseline eGFR and UACR values in these studies suggest that participants were not predominantly at high-risk for CKD progression [80,81]