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Description

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Conclusion In this study, we have identified a ~0.187% level of drug-tolerant persister cells with the CRC cell lines response to anticancer drugs, and we determined that there were G0/G1 cell cycle arrest, and upregulation of stemness factors and mesenchymal-like gene expression in the DTP cells

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The peroxidation of the PUFA chains leads to the destruction of the phospholipid bilayer membrane structure of the cell enhancing membrane permeability, which ultimately leads to cell death [58, 59]

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Patients should report any unexpected injection site reactions, signs of infection, or systemic symptoms to their provider immediately

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