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J Clin Invest 125:24582462 Lei Y, Wen H, Yu Y, Taxman DJ, Zhang L, Widman DG, Swanson KV, Wen KW, Damania B, Moore CB, Giguere PM, Siderovski DP, Hiscott J, Razani B, Semenkovich CF, Chen X, Ting JP (2012) The mitochondrial proteins NLRX1 and TUFM form a complex that regulates type I interferon and autophagy

Nicotine will keep you feeling awake and alert, which can lead to a poor nights sleep, leaving you not only feeling tired but also putting you at risk of developing other health conditions