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Retrieved 2012-03-11

In summary, GLP-2 has a significant inhibitory effect on bone resorption with minimal impact on bone formation, resulting in increased BMD

24 However, since 2008, all non-insulin medications requesting FDA approval for the treatment of T2DM are now expected to prove CV safety alongside glycemic improvements

A dual agonist medication like tirzepatide acts as both a GIP and GLP-1 receptor agonist, potentially offering enhanced benefits for diabetes and weight management