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Mutant FUS R495X dysregulates the expression of genes associated with oxidative mitochondrial metabolism in neurons, and significantly reduces the size of mitochondria, which induces neurotoxicity (Nakaya and Maragkakis, 2018)
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PubMed Sikiric P, Gojkovic S, Krezic I, Smoday IM, Kalogjera L, et al
And ethanol modeling was conducted for a total of 10 weeks
