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Description

Increasing Skeletal Muscle Carnitine Content in Older Individuals Increases Whole-Body Fat Oxidation during Moderate-Intensity Exercise

A phospho-switch controls RNF43-mediated degradation of Wnt receptors to suppress tumorigenesis

This is a 6.75 fold increased in percent weight loss from highest dose to placebo, compared to the 5.9 fold increase seen in the STEP-1 trial

doi: 10.1126/sciadv.aba4353 100 McHughJ

Searches of PubMed, Embase (via OVID), and the Cochrane Library were performed for studies published between January 2015 and May 2025, in accordance with PRISMA 2020 guidelines