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As a result, their unformulated free forms demonstrate minimal cutaneous bioavailability and markedly limited topical pharmacological potential

check out Johannes Konrad's new publication in Acta Biomaterialia: "Interaction mechanisms between antibiotics and calcium phosphate cements as pharmacologically active bone graft substitutes" The study provides a comprehensive analysis of how the two clinically relevant antibiotics, vancomycin and gentamicin, interact with three distinct calcium phosphate cements that form hydroxyapatite in situ

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