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Additionally, the gastrointestinal side effects of Rybelsus may cause dehydration, which could potentially lead to acute kidney injury, particularly in those with pre-existing renal impairment

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[DOI] [PMC free article] [PubMed] [Google Scholar] Burks S., Raymick J., Robinson B., Hanig J., Sarkar S

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The gut-joint axis: microbial dysbiosis and OA Emerging evidence firmly establishes a link between gut microbiota dysbiosis and OA progression, primarily mediated by microbial metabolites via the gut-joint axis. The core protective mechanism involves short-chain fatty acids (SCFAs) like butyrate and propionate, produced from dietary fiber fermentation by commensals such as Bacteroides and Faecalibacterium prausnitzii