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However, toxicity concerns limit their potential use

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Intern Med J 43: 100101, 2013 [DOI] [PubMed] [Google Scholar] 38.Kumar A, Bachhawat AK: A futile cycle, formed between two ATP-dependant -glutamyl cycle enzymes, -glutamyl cysteine synthetase and 5-oxoprolinase: The cause of cellular ATP depletion in nephrotic cystinosis

It is extremely rare for such a tumor to occur in childhood, but, when it does, the excessive GH can cause excessive growth, traditionally referred to as pituitary gigantism