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Immunologically, L-citrulline metabolism participates in macrophage response modulation (69), with its intracellular concentrations being dynamically regulated by immune stimuli such as interferon- (IFN-) and lipopolysaccharide (LPS) ( Figure 2d ) ( Figure 2f ) (70)

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This is a companion Collection with Cardiovascular Diabetology - Endocrinology Reports with the title "Pleiotropic Actions of Incretin-Based Therapies" and with BMC Endocrine Disorders with the title "Incretin-based therapies for cardiometabolic disease: mechanisms and clinical outcome"