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Consequently, increasing the activity of phase II enzymes, such as glutathione S-transferases (GSTs) and NQO-1, may help prevent cancer by enhancing the elimination of potential carcinogens (see the Nrf2-dependent antioxidant pathway) (63)

Indeed, the most well-known TD state is Wernicke-Korsakoff syndrome, first described by Wernicke in a female whose digestive tract was severely damaged by sulfuric acid (53)

doi: 10.1016/j.dsx.2019.06.021, 83

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