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Fingolimod was subsequently demonstrated to be a prodrug analog of sphingosine, becoming phosphorylated into fingolimod-P by sphingosine kinase 2(S1K2), and interacting with S1P receptors on various cell types, outcompeting the native S1P

Maintenance dosing at reduced frequency after initial intensive period

Some patients may experience mild redness or tenderness at the injection site

Patients Planning Surgery If you have an upcoming surgery that requires general anesthesia, inform both your prescribing provider and your surgical team

Addressing reflux can significantly reduce the lump sensation in many patients