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The compound has many similarities to the peptide hormone -melanocyte-stimulating hormone
The full Phase 3 programme, called TRIUMPH, is still running
We did not detect any dierences in the behaviour of the drug-injected mice compared to the controls (Fig.5ac), although there was a trend for shorter open eld centre time in mice that received 0.7 mg/kg dose of bradyzide compared to vehicle controls (p = 0.075, Fig.5a)
The funding institution had no role in the design, conduct, analysis, interpretation, or reporting of the study
Without effective treatments, it is still difficult to demonstrate that such biomarkers could reliably predict therapeutic efficacy or outcomes
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