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Blocking MLCK1 recruitment to the tight junction limits tight junction barrier loss without interfering with essential MLCK functions in epithelial cells and cells of other types

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These include: Dulaglutide: Prescribed as Trulicity for type 2 diabetes (there is no dulaglutide approved for weight management) Semaglutide: Prescribed as Ozempic or Rybelsus for type 2 diabetes and Wegovy for weight management Tirzepatide: Prescribed as Mounjaro for type 2 diabetes and Zepbound for weight management There are also alternatives to GLP-1s, including prescription weight-loss pills like naltrexone/bupoprion and Qsymia, both of which decrease your appetite

Match dosing and schedule to that baseline and to individual goals