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doi:10.1038/s41467-019-10713-z

Some studies have identified metabolic deficiencies in autistic children [14], and it has recently been shown that there is a characteristic metabolic profile in many autistic children involving disturbances in methionine and glutathione metabolism [14, 15]

Holtman IR, Raj DD, Miller JA, Schaafsma W, Yin Z, et al

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It has reported that PQQ exerts its effects through several key molecular mechanisms, including the activation of antioxidant pathways via Nrf2/ARE signaling, enhancement of mitochondrial biogenesis and function through AMPK/PGC-1, and the regulation of inflammatory processes through NF-B inhibition