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Gallbladder Problems: Including gallstones, which can cause severe pain in the upper abdomen, fever, and jaundice

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For this reason, drugs with a long half-life (e.g., amiodarone, elimination t 1/2 of about 58 days) are usually started with a loading dose to achieve their desired clinical effect more quickly

Patients with a history of cholecystectomy (gallbladder already removed) can generally use weight loss injections with lower gallbladder-specific risk, though other biliary tract complications remain possible