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An RCT with 100 SAP patients revealed that combination therapy with vitamin E (400 IU/day) and vitamin C (2 g/day) over 1014 days was associated with a 35% lower incidence of pancreatic necrosis and a 25% reduction in the risk of SIRS (128)

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doi: 10.1016/j.plipres.2022.101165, PMID: [DOI] [PMC free article] [PubMed] [Google Scholar] 61.Chvez-Castillo M, Ortega A, Cudris-Torres L, Duran P, Rojas M, Manzano A, et al