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The Integrative HMP (iHMP) Research Network Consortium

doi: 10.2147/JIR.S353467 304 ZhangT.TsutsukiH.IslamW.OnoK.TakedaK.AkaikeT.et al

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As multiple studies now show an impact of APOE on brain bioenergetics, which occurs prior to the onset of significant AD pathologies ( Materials and methods Animal models In these studies, APOE-TR mice were housed in groups of up to four under standard laboratory conditions at 23 1C, 50 5% humidity, with a 12-h light/dark cycle and access to food and water ad libitum