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Bone turnover marker dynamics VSG induces a consistent activation of bone turnover across age groups, characterized by elevations in both resorption and formation markers

It plays a key role in regulating insulin secretion, appetite, and glucose homeostasis

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After 48 h, biofilms were washed once with 1 PBS and treated using one of the following: 30 mM GSH or 4 g/mL amikacin individually or a combination of 30 mM GSH + 4 g/mL amikacin

Importantly, these changes were observed without significant reductions in food consumption, pointing to enhanced energy metabolism rather than appetite suppression as the primary mechanism