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Other frequently reported issues include: Burping and indigestion (dyspepsia) , which may be uncomfortable and persistent Fatigue , or a general feeling of low energy Heartburn or acid reflux (GERD) Injection site reactions , like redness, itching, or swelling Hair thinning or hair loss , which some patients find surprising Hypersensitivity reactions , which are rare but can include rash, itching, or more serious allergic responses Though these side effects are common, they dont affect everyone, and many people find them manageable compared to the benefits

Youre not trading tolerability for efficacy

On the other hand, GLP-1 RAs were found to alter the gastric/small bowel motility and appetite/satiation via central or parasympathetic (vagal-mediated) pathways, leading to an increased incidence of retained gastric contents (RGCs) with the associated aspiration risk during the perioperative period [6,7,8]

Am J Epidemiol 183:758764

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