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The Therapeutic Potential of Milk Thistle in Diabetes, The Review of Diabetic Studies, US National Library of Medicine, National Institutes of Health

[20] It is important to note that doses higher than 600 mg/day intravenously have not been shown to confer additional clinical benefit, but they may increase side effects

Otte JM, Zdebik AE, Brand S, et al

The combined effect is usually clinically minor but worth monitoring in patients with hypertension or heart disease

Brian Lee, profesor asociado de Medicina en la Escuela de Medicina Keck de la USC en Los ngeles, vot en contra, tras argumentar que el pblico podra interpretar los votos y la aprobacin de la FDA como un respaldo a los productos y que algunos de los compuestos podran no ser mejores que un placebo