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In their letter, they explained that in their own observations of rats who took the drug, they had a 43% average increase in the small intestines length after a 3-month treatment of GLP-1b drugs, pointing out that the clinical trials for Wegovy only tested that for 16 months

Chang, C.-H., Tsai, W.-C., Hsu, Y.-H., & Su Pang, J.-H

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The simple strategy for weekly doses If your trip lasts only a few days, the easiest approach is to take your dose either right before you leave or shortly after you return, especially if this only changes your schedule by a day or two