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The persistent presence of pathogens, such as viruses or bacteria, or their residual components (e.g., the spike protein of SARS-CoV-2), may function as pathogen-associated molecular patterns (PAMPs), continuously activating pattern recognition receptors (PRRs) such as Toll-like receptors (TLRs), thereby providing a potential foundational pro-inflammatory signal (25, 122)

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Ingwall, J

Ongoing basic and translational work, thoughtful trial design, and open reporting are needed to address these controversies

progress has been like this: 1st 2 weeks - no change in dullness, dryness reduced Week 3 - skin started becoming more brighter by week 5 - re