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The FDA advises that compounded drugs should only be used when no FDA-approved alternatives meet a patients medical needs a situation no longer relevant for semaglutide due to the resolved shortage
Dunn J, Liu Y, Banov F, Denison S, Banov D
CagriSema's REDEFINE 1 number is competitive against tirzepatide's SURMOUNT-1 figure, but a direct head-to-head trial reported in February 2026 favored tirzepatide