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Although postsurgical hemorrhages are usually mild, their occurrence, especially in older subjects and toddlers as well as in case of concurrent chronic diseases, may expose the patient to unreasonable risks

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The delayed gastric emptying, whilst therapeutically beneficial for glucose control and weight management, is also responsible for many of the gastrointestinal side effects associated with these medications

The increased risk of thrombosis and heart attack observed in some studies of COX-2 inhibitors may result from this mechanism (Conaghan 2012)

Based on the studys findings, Mahadevan said, prospective studies are needed to see if the findings are similar in real-world cohorts