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This approach moves away from the traditional one-size-fits-all model and instead focuses on personalized, biomarker-guided targeted therapies and best practices tailored to an individual's unique biological profile (263)

Accordingly, weight loss is not clearly improved in studies with a high degree of SGLT2 inhibition (like canagliflozin 300 mg) compared to partial inhibition, for example with empagliflozin 10 mg

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